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Thursday, December 13, 2012
Salmonella
Salmonella is a genus of rod-shaped, Gram-negative,
non-spore-forming, predominantly motile enterobacteria with diameters
around 0.7 to 1.5 µm, lengths from 2 to 5 µm, and flagella that
grade in all directions. They are chemoorganotrophs, obtaining their
energy from oxidation and reduction reactions using organic sources,
and are facultative anaerobes. Most species produce hydrogen sulfide,
which can readily be detected by growing them on media containing
ferrous sulfate, such as TSI. Most isolates exist in two phases: a
motile phase I and a nonmotile phase II. Cultures that are nonmotile
upon primary culture may be switched to the motile phase using a
Cragie tube. Salmonella is closely related to the Escherichia genus
and are found worldwide in cold- and warm-blooded animals (including
humans), and in the environment. They cause illnesses such as typhoid
fever, paratyphoid fever, and foodborne illness. The organism enters
through the digestive tract and must be ingested in large numbers to
cause disease in healthy adults. Gastric acidity is responsible for
the destruction of the majority of ingested bacteria. Salmonellosis
is a disease caused by raw or undercooked food. Infection usually
occurs when a person ingests foods that contain a high concentration
of the bacteria, similar to a culture medium. However, infants and
young children are much more susceptible to infection, easily
achieved by ingesting a small number of bacteria. In infants,
contamination through inhalation of bacteria-laden dust is possible.
After a short incubation period of a few hours to one day, the germs
multiply in the intestinal lumen, causing an intestinal inflammation
with diarrhea that is often mucopurulent and bloody. In infants,
dehydration can cause a state of severe toxicosis. The symptoms are
usually mild. Normally, no sepsis occurs, but it can occur
exceptionally as a complication in weakened or elderly patients.
Extraintestinal localizations are possible, especially Salmonella
meningitis in children, osteitis, etc. Enteritis Salmonella can cause
diarrhea, which usually does not require antibiotic treatment.
However, in people at risk such as infants, small children, the
elderly, Salmonella infections can become very serious, leading to
complications. If these are not treated, HIV patients and those with
suppressed immunity can become seriously ill. Children with sickle
cell anaemia who are infected with Salmonella may develop
osteomyeletis. In Germany, Salmonella infections must be reported.
Between 1990 and 2005, the number of officially recorded cases
decreased from approximately 200,000 to approximately 50,000 cases.
Every fifth person in Germany is thought to carry Salmonella. In the
USA, about 40,000 cases of Salmonella infection are reported each
year. According to the World Health Organization, over 16 million
people worldwide are infected with typhoid fever each year, with
500,000 to 600,000 fatal cases. Salmonella bacteria can survive for
weeks outside a living body, and they are not destroyed by freezing.
Ultraviolet radiation and heat accelerate their demise; they perish
after being heated to 55 C (131 F) for 90 min, or to 60 C (140 F) for
12 min. To protect against Salmonella infection, heating food for at
least ten minutes at 75 C (167 F) is recommended, so the center of
the food reaches this temperature. So You see salmonella is a very bad infection that anyone can get to avoid salmonella always make sure to cook food at the time it says to cook.
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